Friday, 25 November 2011

3-D Structure Analysis-Domain Prediction, Globularity and Assembly Analysis


pDomain resource is centered around defining structural domains from 3D coordinates. This resource brings together current state-of-the-art algorithmic methods for partitioning proteins into domains.
Search for Conserved Domains within a protein sequence.
Dompred is a server designed to predict putative protein domains and their boundaries for a given protein sequence. The server uses several methods, from identifying obvious similarities to Pfam-A domain sequences to predicting domains using DomSSEA in cases where sequence searching has yielded no results.
The approach 'Protein Peeling' aims at cutting the 3D protein structure into a limited set of 'Protein Units'. A more precise definition of protein unit is a compact sub-region of the 3D structure corresponding to one sequence fragment.
DOMpro is a web server to predict protein domain boundaries using 1D-Recursive Neural Networks and statistical methods.
DIAL is a web server for the automatic identification of structural domains given the three-dimensional coordinates of a protein.
Intrinsic Protein Disorder, Domain & Globularity Prediction
PURE is a bioinformatics protocol to identify putative domains in the Unassigned Regions.
Prediction of Protein Domains at University College Dublin.
Domain 3D is a method developed by Willie Taylor to identify globular domains in protein structure.
DHcL (Domain Hierarchy and closed Loops)is a server for the analysis of basic structural units of a protein. The server calculates domain structures at different levels of energy hierarchy and elements of the loop-n-lock structure, closed loops and van derWaals locks.

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