Computational methods for molecular diagnostics of cancer

Institution:

Cancer Research UK

Dept/School/Faculty:

Cambridge Research Institute

PhD Supervisor:

Dr N Rosenfeld

Application Deadline:

20 December 2011

Funding Availability:

Funded PhD Project (Students Worldwide)

The group's aim is to develop novel diagnostic tools for cancer through the application of emerging molecular and genomic technologies. The current focus of research is on circulating tumour-specific DNA as a non-invasive modality to assess disease progression and response to therapy.

We use genomic platforms to identify somatic mutations and structural rearrangements in tumour samples, and develop assays to measure the presence of tumour-specific sequences. We apply these to monitor the levels of cell-free tumour DNA in serial blood samples collected from patients during treatment and clinical follow-up.

We integrate and innovate a variety of state-of-the-art methods including microfluidic digital PCR, paired-end next generation sequencing and targeted resequencing. We use these to collect novel types of molecular data. The proposed project involves the analysis of such novel data, in conjunction with concurrent clinical information, to develop clinically meaningful diagnostic classifications. An additional goal is to support genomics analysis that forms an integral part of ongoing projects.

A successful candidate is expected to have enthusiasm and facility for computational analysis, a solid grounding in statistical approaches and familiarity with molecular biology concepts. Experience in analysis of experimental data in the physical or life sciences is advantageous.

Projects in our laboratory are highly interdisciplinary relying on close collaboration between experimentalists, clinicians and analysts, and thus demand good interpersonal skills, cooperation, independence, and scientific maturity.

Apply 

RASA LSI ,Pune inviting application for Research trainee/industrial training/Projects in Bioinformatics, Chemoinformtics, Drug Designing, Microarray data analysis,molecular modelling and dynamics || 100% job guarantee program in Software Development

"Make your Carrier in Life science by Joining RASA"

RASA launching Job Oriented Training programs

RASA Life Science Informatics, a Bio-Chemoinformatics company based in Pune, provides unmatchable training facilities to students and professionals in Life Science Informatics. We are now launching a 100% Job oriented Training program, Academic & Industrial Projects to enable anyone and everyone to get trained and get placed.

Achievements of RASA

• RASA trained biochemistry, microbiology, biotech students in Bioinformatics/ Chemoinformatics & Software Development to enhance & optimize their research & Publication work.
• We are first one to provide corporate training in Bioinformatics / Chemoinformatics to Wipro.
• We also successfully conducted a workshop with Persistent under Biocrat on “Insilico Drug Discovery”.
• Local Newspaper also appreciated our initiative to promote Bioinformatics / Chemoinformatics in India in a practical way.
• We trained around 90 personals from different background in Bioinformatics and chemoinformatics.
• RASA is a pioneer in providing ’in demand’ job & research oriented training & projects.
• RASA have successfully trained scientist and professionals from NCL, NARI BCIL, Persistent, Evolves, D Y patil, and other reputed national institutes & companies. 
• RASA audience pool ranges from Junior college to PhD holders.
• 90% students get placed after training from RASA across India & abroadin various Pharma , biotech,CRO,  institutes & companies like Xceleris, Evolvus,  NCL & in RASA itself.

Benefits of joining RASA:

• RASA is BCIL recognized company.

• Science Skills Development-

  • These Industrial training programs enable students to better understand science and perform better during interviews. As practical skilled knowledge is the most important aspect of technology driven science like Bioinformatics, Chemoinfromatics, Biotechnology & many more.

• Emphasis on concept building of students.-

  • We  design our courses in a way which emphasis maximum on knowledge building and innovations, we see each of our trainee as a future entrepreneur, running an organization based on his/her ideas and experiences.

• Different Programs as per Individual Needs -

  • This year for the first time we are offering four different project internship programs in different areas with limited number of seats to maximize the personal needs of students and to give him/her most in form of working knowledge

• Acquiring Latest Knowledge-

  • It helps in early identification of career trends with higher salary packages.

• 90%of RASA Trained persons are in industry or research

• Explore career opportunities in academia by experiencing the excitement, frustration, and challenges of scientific research and gain an insight into what a career in the science entails.
   
• Selected student will get a chance of Publication in one of the peer reviewed journals, if one’s work matches the required standards.
   
• Hands-on and training and research experience exposure to the research field.

• 100% Job & research Assistance.

• Candidates have high chances of getting absorbed into many MNCs or in RASA itself.

  • We intent to restrict maximum number of students to 6 only.
  • We conduct batches on week ends also.
  • Guest lecture & guidance from eminent scientist from research institute of India and abroad.
  • Guidance throughout the training period.
  • Help in making attractive CV.
  • Excellent infrastructure.

• Experienced faculty from industry, academia.

  • Sameer Chaudhary (MD of RASA,5 yrs exp in Bio-&Chemoinformatics)
  • Sapana Mehendale (M D, RASA,4 yrs exp in life science software development)
  • Dr. Muthukumarasamy Karthikeyan (Scientist E1,NCL,15 yrs exp in Chemoinformatics &  Drug Discovery Research)
  • Dr. Rajesh Kumar Singh (Scientist,NCL,15 yrs exp in Molecular Biology, Biotech, protein crystallography )
  • Dr. Syed Ismail Ahson (Pro VC, Patna University,55 yrs exp in Computer science Bio/Chemoinformatics)
  • Pradeep Malji (Engineer, KSB Tech Pvt. Ltd, 4 years  exp Software Design and Development, Technical Support)
  • Saurabh Bundela (Senior Scientist, Systems Biology Worldwide,11 yrs exp in Genomics, proteomics, Bioinformatics)
  • Vishal Rajdev(Senior S/w Executive, Thermax,6 yrs exp in Database management & ERP)

RASA Exclusive Research Trainee Module:

• Applications are invited for the Research Trainee Positions in the field of Micro array data analysis/Computer added Drug Designing/Molecular Modeling & Dynamics/System Biology / Software Development.

Benefits of Research Trainee Programme:

Students being selected for the entire package for a period of 6 months will get the following lucrative offers:

• Upon completion of the above mentioned training & project, student will be awarded with an ‘Industrial working experience letter’ as a Research Trainee in the selected field from RASA, along with the certificates of each of the completed training modules.
• Selected candidate intimate with anappointment letter on their selection for above mention posts.
• Student will getone Training Module FREE under the same.
• Students can also get 100% Job Assistance.
• Selected students will get a chance to work in industrial environment.
• Selected student will get a chance of Publication in one of the peer reviewed journals, if one’s work matches the required standards.

Why Industrial Training /Project:

• To meet corporate/research need to get hire easily.
• To channelize efforts in right direction.
• To optimize knowledge and skills.
• To be out performer from day one on work. 

RASA Industrial Training/Project modules

RASA provide summer/winter/industrial certification courses and projects of duration 1 month to 6 months in field of Bioinformatics/Chemoinformatics & Software Development. These training/project modules will enable the candidate to develop skills that will provide them confidence and skills to enter any Biotech, Bioinformatics, Pharmacy, Research & Development software and Life science industry.

Project students will get the following lucrative offers:

• 10-15 days of training on project topic
• Guest Lectures from eminent scientist and professional.
• Chance of publication.
• 100% Job Assistance .
• Assured Job’s interview calls.
• HR & Personal Development & soft skill training during project .

Intensive Industry-oriented training and project Topics are as follows:

• Chemoinformatics
• Computer Aided Drug-designing
• Molecular modeling and Dynamics
• Docking Studies
• QSAR
• vHTS and Scaffold Hopping
• Workflow Development
• Bioinformatics
• In-silico Primer Designing
• Homology Modeling and Docking
• Microarray Data-analysis
• Software development
• JAVA/BioJAVA/ChemJAVA
• Perl/BioPerl 
• Web Portal development

Hurry up !!

We just have 6 seats for each Training /Project Module

Which are filling up fast on a first come first serve basis

Important details:

Research Trainee Module

Classes start from:  1^st Batch will be start from – 15^th December  2011

                                    2^nd Batch will be start from – 15^th  Jan  2012

                                    3^rd Batch will be start from – 15^th Feb  2012

Group Discount:      Group of 2 Students will get 5% of discount on Total fee.

                                    Group of 4 Students will get 10% of discount on Total fee.

                                    Group of above 5 Students will get 15% of discount on Total fees

Note: To know feed back of RASA Trained students please visit http://www.facebook.com/pages/RASA-Life-Science-Informatics/167189876657972?ref=ts

RASA  Placement Record

For any query please feel free to contact us onProgram-Coordinator

RASA Life Science Informatics , 
301,Dhanashree construction,
opp Chitaranjan vatika, 
Model colony,Shivaji nagar,
Pune 411016.
Phone:  020 – 65600408  , 08007594458 Email: info@rasalsi.com

www.rasalsi.com

Research Scientist in Neurogenomics/Bioinformatics : Nijmegen, Netherlands

The Max Planck Institute for Psycholinguistics (Nijmegen, the Netherlands) is offering a Research Scientist position in the innovative area of Neurogenomics/Bioinformatics.

The MPI in Nijmegen is one of the leading research institutes in the world, with a very stimulating environment, excellent facilities and resources. The Language & Genetics Department at the MPI uses state-of-the-art methods and cutting-edge technologies to trace the connections between genes, neuronal and brain functions, and behavior. Moreover, we benefit from close connections with expert teams in neuroscience and brain imaging at the Donders Institute for Brain, Cognition and Behaviour, and in human genetics at the Human Genetics Department of Radboud University.

We are seeking a research scientist who holds either a masters or PhD qualification to work with the department on a range of bioinformatics and neurogenomics projects. Candidates do not require prior experience in neuroscience, but should be keen to learn and involve themselves in the ongoing research of the department, which is focused on genetics of the neuron, brain, behavior and cognition. For further details see our website: http://www.mpi.nl/research/research-projects/language-and-genetics-project

Candidates should be skilled in a discipline such as computer science or programming in relation to biostatistics or interrogation of genomics datasets, and have knowledge of data-analytical approaches in one (or more) of the following areas:

• a. Analysis of genome-wide association datasets, for example gene network/pathway approaches, expression QTLs.
• b. Next-generation-sequencing studies such as exome screening, RNA-Seq or ChIP-Seq
• c. Bioinformatics with genomics (computational and analytic skills suited to large scale, multi-dimensional datasets)
• d. Integrated analysis of genetic, gene expression, and other functional genomics datasets, such as gene ontology and network analysis

Duration : The position is available from early 2012. The term of appointment is for three years, with a salary according to the German TVöD. Scientists in the Netherlands report among the highest job satisfaction ratings of any in the world.

Applications should include :(i) A brief cover letter summarizing your interests 
(ii) a CV;
(iii) the names, email addresses and contact numbers of three referees who would be willing to provide letters of recommendation;

Send applications or enquiries to : E-mail: martina.bernhard@mpi.nl

Contact : 
Martina Bernhard (Secretary to Dr S Fisher, Director)
Language & Genetics Dept
Max Planck Institute for Psycholinguistics
Wundtlaan 1
6525 XD Nijmegen
The Netherlands

Deadline : 28.01.2012

Training Course on "New Frontiers in Molecular Biology" at MIET, Meerut

Training Course onNew Frontiers in Molecular Biology16 - 29  December, 2011Organized byDepartment of BiotechnologyMeerut Institute of Engineering & Technology (MIET), Meerut

Envisioning the requirement of technically skilled manpower in the current era of Industrial growth, the Department of Biotechnology was established in 2001 as a pioneer step. The department offers courses like B.Tech., M.Tech. (Biotechnology) & M. Tech. (Bioinformatics). We are the first In UPTU to introduce M.Tech. Bioinformatics in 2009. MIET Biotechnology Laboratories are well equipped with state of the art facilities for conducting modern research. The department has highly qualified and experienced faculty members Who along with students are actively involved in various academic and research projects for the coninuous development in the field of Biotechnology.

Program Coverage :a. Vaccine design & development 
b. Recombinant DNA Technology 
c. RNAi, Microarray
d. Knockout Animal models
e. Ion Channels

Eligibility & registration :

• Faculty from AICTE approved institutions are eligible to participate. 
• No registration fee is charged for the ymnicipation since the programme Is fully sponsored by AICTE. New Delhi. Besides. TA will be provided to the eligible pouticipants.

Address for Correspondence :Prof. A. Subrahrnanyam (Course Convener) 
Department of Biotechnology
NH-58. Bypass Road, 
Bzaghpat Crossing Meerut 250005 (Uttar Pradesh)  
Email : dbt.miet@gmail.com
Mob: 09917707000.04537102999
09308591622. 09412 162179

Deadline : 10.12.2011

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