Proteomics was thought to be a natural extension after the field of
genomics has deposited significant amount of data. However, simply
taking a straight verbatim approach to catalog all proteins in all
tissues of different organisms is not viable. Researchers may need to
focus on the perspectives of proteomics that are essential to the
functional outcome of the cells. In Integrative Proteomics, expert
researchers contribute both historical perspectives, new developments in
sample preparation, gel-based and non-gel-based protein separation and
identification using mass spectrometry. Substantial chapters are
describing studies of the sub-proteomes such as phosphoproteome or
glycoproteomes which are directly related to functional outcomes of the
cells. Structural proteomics related to pharmaceutics development is
also a perspective of the essence. Bioinformatics tools that can mine
proteomics data and lead to pathway analyses become an integral part of
proteomics. Integrative proteomics covers both look-backs and look-outs
of proteomics. It is an ideal reference for students, new researchers,
and experienced scientists who want to get an overview or insights into
new development of the proteomics field.
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