Two PhD Fellowships in RNA Bioinformatics
Added on
Nov 3, 2011
Employer description
Center for non-coding RNA in Technology and Health (RTH), http://rth.dk, was established in 2010 to take a multi-disciplinary research strategy in the area of non-coding RNAs. The Center has two open PhD positions in Bioinformatics with putative start 1 January 2012 or as soon as feasible. The duration of each position is three years. New application deadline: 5 December 2011.Background
Within recent years, it has become evident that non-coding RNAs (ncRNAs) play numerous important roles in the cell. Many ncRNAs contain a characteristic RNA structure, a hallmark that (albeit often at a high computational cost) can be exploited in in silico screens. These screens are in essence based on search for the RNA secondary structure.
Job description
The two PhD projects are motivated in the further analysis of in silico generated ncRNA candidates and the goal is to develop computational methods to predict RNA-RNA interactions with the aim of genome-wide applications and emerging interaction networks containing non-coding RNAs. The projects will focus on constructing methods for RNA-RNA interactions as well as on designing methods for RNA interference while taking the accessibility into account. A part of the projects will involve collaboration with Exiqon A/S on interactions to LNA. It is expected that the methods can gain from the use of the multiple sequences (comparative analysis), available 3D structure information as well as transcriptomic data.Both positions will be in collaboration with people in Center for non-coding RNA in Technology and Health.
Job requirements
The applicant should hold professional as well as personal skills and qualifications as stated below:- A master degree in Bioinformatics, computational biology, biology, statistics, or similar.
- Experience with algorithm development.
- Experience with Perl or Python (or similar).
- Experience with C, C++ and/or Java.
- Possess good interpersonal skills.
- Be excellent in speaking and writing in English.
- General knowledge of RNA structure and folding, RNA gene search algorithms, and algorithms for structural alignment of RNAs and RNA-RNA interactions.
- Insight in statistics.
Job benefits
The positions will be filled according to the Agreement between the Danish Ministry of Finance and the Danish Confederation of Professional Associations. Each post is covered by the Protocol on Job Structure.The PhD positions require the applicant to be approved for admission to the PhD programme at LIFE when accepted for the positions.
The average annual salary for PhD students is currently DKK 372 000 (approx. Euro 49 600). In addition, the successful candidates will enter a pension fund scheme as well as paid holidays after one year. Operating costs such as course fees, project expenses, travel and stays abroad, etc. are subsidized by the project.
Apply information
Click here to access the University's online application system.Applications - in English - should include:
- Cover Letter applying for and detailing your motivation and background for applying
- CV
- Diploma and transcripts of records
- Other information for consideration, e.g. list of publications (if any), peer reviewed and other
- Personal Recommendations
- A maximum of 3 relevant scientific works which the applicant wishes to be included in the assessment.
The applications must be received latest by 5 December 2011. Applications received after the closing time will not be considered.
For further information about the post, please contact Main Supervisor:
Prof. Jan Gorodkin, e-mail: gorodkin@rth.dk, phone: +45 3533 4704, +45 3533 3578 (direct).
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